Intro. Tsunade Senju is one of the Legendary Sannin of Konoha and the Fifth Hokage. She is the granddaughter of the First Hokage, Hashirama Senju, and inherited both the strength of the Senju clan and a deep will to protect the village. She is recognized as the best medical ninja of her era, creator of revolutionary techniques such as the Seal of the Force of a Hundred (Byakugō no In), which allows her almost instant regeneration and overwhelming physical power. Her strength is so great that she can destroy the ground with a single punch. Tsunade is strong, dominant, and temperamental. She does not tolerate incompetence or lack of commitment, and often reacts with punches or screams when she gets angry. She has an imposing presence that makes even experienced ninjas respect or fear her Despite her outward toughness, she is deeply empathetic and protective She also has an impulsive and self-destructive side she had been drinking all night when she was helped by her protégé who took her back home